Cardioprotective Effects Induced by Preconditioning with Halogenated Anesthetics
نویسندگان
چکیده
منابع مشابه
Halogenated Anesthetics and Human Myocardium
THE effects of halogenated anesthetics on the myocardium have been studied extensively in vivo and in vitro in various animal species. In the past, investigators have focused their efforts on heart function, myocardial mechanics, and electrophysiology. During recent years, considerable knowledge has been obtained by new investigative methodologies, including molecular and cellular biology and a...
متن کاملHepatotoxicity of Halogenated Inhalational Anesthetics
CONTEXT Halogenated inhalational anesthetics are currently the most common drugs used for the induction and maintenance of general anesthesia. Postoperative hepatic injury has been reported after exposure to these agents. Based on much evidence, mechanism of liver toxicity is more likely to be immunoallergic. The objective of this review study was to assess available studies on hepatotoxicity o...
متن کاملIntravenous emulsified halogenated anesthetics produce acute and delayed preconditioning against myocardial infarction in rabbits.
BACKGROUND Preconditioning against myocardial infarction by volatile anesthetics is well known. The authors tested the hypothesis that new emulsified formulations of halogenated anesthetics administered intravenously reduce myocardial infarct size when administered either 1 or 24 h before prolonged ischemia and reperfusion. METHODS Pentobarbital-anesthetized rabbits (n = 39) were instrumented...
متن کاملhepatotoxicity of halogenated inhalational anesthetics
conclusions hepatotoxicity of halogenated inhalational anesthetics has been well documented in available literature. halothane-induced liver injury was extensively acknowledged; however, the next generation halogenated anesthetics have different molecular structures and associated with less hepatotoxicity. although anesthesia-induced hepatitis is not a common occurrence, we must consider the as...
متن کاملAnesthetics, cerebral protection and preconditioning.
BACKGROUND AND OBJECTIVES Several studies demonstrate that cerebral preconditioning is a protective mechanism against a stressful situation. Preconditioning determinants are described, as well as the neuroprotection provided by anesthetic and non-anesthetics agents. CONTENT Review based on the main articles addressing the pathophysiology of ischemia-reperfusion and neuronal injury and pharmac...
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ژورنال
عنوان ژورنال: Journal of Interdisciplinary Medicine
سال: 2016
ISSN: 2501-8132
DOI: 10.1515/jim-2016-0006